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Publications

KGK Science Inc. has conducted more than 200 studies over our 20 years in business. We are proud to present the work we have achieved with our clients. The following publications are a sample of our continuously growing body of clinical research publications.

Publications:

Fouad, G., Evans, M., Barss, S., Baisley, J., Crowley, D., & Guthrie, N. (2008). Safety and tolerability of iron amino acid chelate in premenopausal women. Faseb Journal, 22.

Evans, M., Baisley, J., Barss, S., & Guthrie, N. (2009). A randomized, double-blind trial on the bioavailability of two CoQ10 formulations. Journal of Functional Foods, 1(1), 65-73.

Moyad, M. A., Combs, M. A., Crowley, D. C., Baisley, J. E., Sharma, P., Vrablic, A. S., & Evans, M. (2009). Vitamin C with metabolites reduce oxalate levels compared to ascorbic acid: A preliminary and novel clinical urologic finding. Urologic Nursing : Official Journal of the American Urological Association Allied, 29(2), 95-102.

Moyad, M. A., Combs, M. A., Crowley, D. C., Baisley, J. E., Sharma, P., Vrablic, A. S., & Evans, M. (2009). Vitamin C with metabolites reduce oxalate levels compared to ascorbic acid: A preliminary and novel clinical urologic finding. Urologic Nursing : Official Journal of the American Urological Association Allied, 29(2), 95-102.

Nakao, A., Toyoda, Y., Sharma, P., Evans, M., & Guthrie, N. (2010). Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. Journal of Clinical Biochemistry and Nutrition, 46(2), 140-149.

Rumberger, J. A., Napolitano, J., Azumano, I., Kamiya, T., & Evans, M. (2011). Pantethine, a derivative of vitamin B5 used as a nutritional supplement, favorably alters low-density lipoprotein cholesterol metabolism in low- to moderate-cardiovascular risk north american subjects: A triple-blinded placebo and diet-controlled investigation. Nutrition Research, 31(8), 608-615.

Wilson, D., Evans, M., Guthrie, N., Sharma, P., Baisley, J., Schonlau, F., & Burki, C. (2010). A randomized, double-blind, placebo-controlled exploratory study to evaluate the potential of pycnogenol® for improving allergic rhinitis symptoms. Phytotherapy Research, 24(8), 1115-1119.

A Randomized, Double-blind, Placebo Controlled, Parallel Group Trial to Investigate the Safety and Efficacy of Labisia pumila Water Extract (BIO LP101) in Healthy Females*

Bays, H. E., Evans, J. L., Maki, K. C., Evans, M., Maquet, V., Cooper, R., & Anderson, J. W. (2013). Chitin-glucan fiber effects on oxidized low-density lipoprotein: A randomized controlled trial. European Journal of Clinical Nutrition, 67(1), 2-7.

Evans, M., Sharma, P., & Guthrie N. (2010). A randomized, double-blind, crossover study on the pharmacokinetics of a novel formulation of CoQ10 with pyridoxal 5′-phosphate and phosphatidyl choline. Journal of Dietary Supplements, 7, 314–324.

Evans, M., Kalman, D., Alvarez, P., Paquet, M., & Guthrie, N. (2014). A randomized, double-blind, placebo-controlled clinical trial evaluating dermytol(®) cream for the treatment of actinic keratoses. Clinical, Cosmetic and Investigational Dermatology, 7, 215-224.

Evans, M., Reeves, S., & Robinson, L. E. (2012). A dried yeast fermentate prevents and reduces inflammation in two separate experimental immune models. Evidence-Based Complementary and Alternative Medicine, 2012.

Evans, M., Elliott, J. G., Sharma, P., Berman, R., & Guthrie, N. (2011). The effect of synthetic genistein on menopause symptom management in healthy postmenopausal women: A multi-center, randomized, placebo-controlled study. Maturitas, 68(2), 189-196.

Evans, M., Guthrie, N., Pezzullo, J., Sanli, T., Fielding, R., & Bellamine, A. (2017). Efficacy of a novel formulation of L-carnitine, creatine, and leucine on lean body mass and functional muscle strength in healthy older adults: A randomized, double-blind placebo-controlled study. Nutrition & Metabolism, 14(1).

Evans, M., Beck, M., Elliott, J., Etheve, S., Roberts, R., & Schalch, W. (2013). Effects of formulation on the bioavailability of lutein and zeaxanthin: A randomized, double-blind, cross-over, comparative, single-dose study in healthy subjects. European Journal of Nutrition, 52(4), 1381-1391.

Evans, M., Wilson, D., & Guthrie, N. (2014). A randomized, double-blind, placebo-controlled, pilot study to evaluate the effect of whole grape extract on antioxidant status and lipid profile. Journal of Functional Foods, 7(1), 680-691.

Evans, M., Salewski, R., Christman, M., Girard, S., & Tompkins, T. (2016). Effectiveness of lactobacillus helveticus and lactobacillus rhamnosus for the management of antibiotic-associated diarrhoea in healthy adults: A randomised, double-blind, placebo-controlled trial. British Journal of Nutrition, 116(1), 94-103.

Wilson, D., Evans, M., Weaver, E., Shaw, A. L., & Klein, G. L. (2013). Evaluation of serum-derived bovine immunoglobulin protein isolate in subjects with diarrhea-predominant irritable bowel syndrome. Clinical Medicine Insights: Gastroenterology, 2013(6), 49-60.

Evans, M., Rumberger, J. A., Azumano, I., Napolitano, J. J., Citrolo, D., & Kamiya, T. (2014). Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: A triple-blinded placebo and diet-controlled investigation. Vascular Health and Risk Management, 10, 89-100.

Forssten, S., Evans, M., Wilson, D., & Ouwehand, A. C.(2014). Influence of a probiotic mixture on antibiotic induced microbiota disturbances. World Journal of Gastroenterology, 20(33), 11878-11885.

Fouad, G.T., Evans, M., Sharma, P., Baisley, J., Crowley, D., & Guthrie, N.(2013). A randomized, double-blind clinical study on the safety and tolerability of an iron multi-amino acid chelate preparation in premenopausal women. Journal of Dietary Supplements, 10, 17–28.

Evans, M., Sharma, P., and Guthrie, N. (2012). Bioavailability of Citrus Polymethoxylated Flavones and Their Biological Role in Metabolic Syndrome and Hyperlipidemia. In Readings in Advanced Pharmacokinetics— Theory, Methods and Applications, A. Noreddin, ed. (InTech). http://dx.doi. org/10.5772/34087. http://www.intechopen.com/books/readings-in-advancedpharmacokinetics-theory-methods-and-applications/the-bioavailability-ofcitrus-polymethoxylated-flavones.

Rubin, K. H., Matusheski, N. V., Evans, M., Guthrie, N., & Black, R. M.(2009). A modified carbohydrate diet, including uniquely formulated meal and snack products, results in weight loss and improvement in lipid profile compared to a reduced calorie diet. Faseb Journal, 23(1).

Annie, G., Dale, W., Azreena, A., & Malkanthi, E. (2014). Safety and efficacy of a labisia pumila var alata water extract on sexual well being and lipid profile of pre- and postmenopausal women: A randomized double-blind pilot study. African Journal of Biotechnology, 13(6), 768-777.

InterHealth Nutraceuticals, Inc. | Oct 13, 2008. (2008, October 13). New Clinical Study Shows UC-II® is More than Twice as Effective as Glucosamine Chondroitin. Retrieved April 26, 2017, from http://www.newhope.com/supplements/new-clinical-study-shows-uc-ii-more-twice-effective-glucosamine-chondroitin

Daiichi Fine Chemical Co., Ltd. of Japan. (2008, September 24). Leading Cardiologist Joins Ontario Research Firm to Conduct New Clinical Trial on the Effect of Pantethine on Cholesterol Levels. Retrieved April 26, 2017, from http://www.prnewswire.com/news-releases/leading-cardiologist-joins-ontario-research-firm-to-conduct-new-clinical-trial-on-the-effect-of-pantethine-on-cholesterol-levels-65147412.html

Evans, M., Wilson, D., & Guthrie, N. (2014). Efficacy of a natural mineral complex in north american adults with osteoarthritis of the knee: A randomized double-blind placebo-controlled study. Open Access Rheumatology: Research and Reviews, 6, 91-103.

Crowley, D. C., Lau, F. C., Sharma, P., Evans, M., Guthrie, N., Bagchi, M., Raychaudhuri, S. P. (2009). Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: A clinical trial. International Journal of Medical Sciences, 6(6), 312-321.

Evans, M., Paterson, E., & Barnes, D. (2014). An open label pilot study to evaluate the efficacy of spanish black radish on the induction of phase I and phase II enzymes in healthy male subjects. Bmc Complementary and Alternative Medicine, 14(1), 475-475. 

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